Category

PRP

Reversing Hair Loss with PRP

By | Blog, PRP, women's health

By Dr. Emilia A. Ripoll

Bald is beautiful

Think about how different the world would we be without the contributions of these great bald men: Hippocrates, Leonardo da Vinci, Galileo, William Shakespeare, Charles Darwin, George Washington, Ben Franklin, Winston Churchill, Dwight Eisenhower, Pablo Picasso, Mahatma Gandhi, Mikhail Hair PRP 3Gorbachev, or The Dalai Lama.

Although I’ve never polled my patients, it’s a safe bet that men would prefer to keep their hair if they could — or Rogaine sales would not be pushing $50 million a year. For better or worse, there’s a global stigma about hair loss that makes many men feel diminished, emasculated, self-conscious, or just plain old. Have you ever heard a man say, “I can’t wait until my hair falls out so I can start shaving my head”?

Neither have I.

Bald may be beautiful, but it’s not for everyone — especially women

Although I have seen some women who look good with very short hair, like most women, I have a strong attachment to my hair. It’s part of what makes me feel feminine. So why on earth would I want to lose it?

Imagine my delight as a doctor at discovering a new application of PRP (platelet rich plasma) therapy that not only reverses hair loss (alopecia), but actually stimulates the growth of new hair. It’s a blessing to be able to offer this breakthrough treatment to my male and female patients who suffer from hair loss — and at a huge savings over the cost of hair transplants.

Before I jump into how PRP therapy regrows hair, allow me to explain what happens when hair loss occurs.

What causes hair loss?

Hair loss is part of everyday life. According to the American Academy of Dermatology, most people lose anywhere from 50 to 100 strands of hair every day.

All your hair follicles, including the ones on your head, go through a three-phases cycle:

  1. Growth (anagen)
  2. Resetting (catagen)
  3. Resting (telogen)

At any given time, different follicles are in different phases. Usually, about 90 percent of your follicles are in the anagen, or growth, phase.

“Hair loss” occurs when you start losing more hair than you grow back. “Baldness” happens when hair loss becomes noticeable. Both hair loss and baldness occur in men and women.

Male pattern baldness and female pattern baldness also have a genetic hormonal component. (You can thank your parents, and their parents, and their parents….) And you inherit it from both sides of your family — not just your mother’s side — so you can stop blaming your mom.

Male pattern baldness, which starts with a receding hairline at the temples, can begin during teenage years; whereas, female pattern baldness (thinning hair at the front, sides, and crown of the head) usually starts after menopause. Although, female pattern baldness may start as early as mid-20s, these cases are rare.

There are five basic types of hair loss (alopecia)

1. Androgenetic alopecia: male pattern hair loss in men, and female pattern baldness in women

2. Alopecia areata: This condition is considered an autoimmune disorder because white blood cells attack the hair follicles, causing hair to fall out in a circular pattern. Typically, the hair grows back within a couple of months. A sudden increase in stress (death of a loved one, financial instability, a sick child, and so on) can be a factor in Alopecia areata.

3. Telogen effluvium: In this condition, the hair follicles get stuck in the contracted resting (telogen) phase and have trouble returning to the expansive growth (anagen) phase. Telogen effluvium often occurs after major surgery (a reaction to anesthesia), dramatic weight loss, extreme stress, and pregnancy.

4. Other Medical Conditions: Diabetes, lupus, thyroid disorders can all cause/contribute to hair loss.

5. Nutrition: Diets that are low in protein, iron, zinc, and certain vitamins (A, B6, B12, C, and D) can all cause hair loss. Too much insulin in the blood (hyperinsulinemia) and insulin resistance (when increased amounts of insulin are required to move sugar from the blood into the cells) can contribute to alopecia. These conditions are frequently the result of eating a high-carbohydrate diet.

Restrictive hairstyles like cornrows and tight braids, hair dyes, chemical treatments, even blow drying can all cause temporary hair loss. Fortunately, the hair usually grows back once you stop torturing it to death.

DHT is the culprit

As I mentioned earlier, both male and female pattern baldness have a strong genetic component. These types of baldness are caused by individual hair follicles responding to dihydrotestosterone (DHT). DHT is a more potent form of testosterone that is responsible for body and facial hair in men and women and prostate growth in men. (Yes, women have testosterone in their bodies, just like men have estrogen in theirs.)

The reason female pattern baldness usually doesn’t occur until perimenopause or menopause is because women have enough estrogen circulating in their bodies to offset the presence of DHT. As a women’s estrogen levels decline, however, hair follicles are “unprotected” and DHT has more of an unwanted impact.

Although the exact biochemical pathway by which DHT adversely affects hair follicles in genetically prone scalps is poorly understood, DHT attacks the hair follicle and contracts the follicle and it’s opening to the point of turning a normal strand of hair into peach fuzz.

DHT also shortens the anagen phase of hair growth until the follicles switches first to the catagen and then to the telogen phase. The follicle curls up like a puppy in its bed and goes to sleep — and stays asleep. Essentially, PRP wakes the puppy up.

PRP restores hair loss

Instead of reversing the effects of DHT on the hair follicles of the scalp, PRP rejuvenates the surrounding tissues via the introduction of various platelet-derived growth factors.

These growth factors (a special group of proteins that the body uses in wound healing) stimulate stem cells in the scalp to produce new tissues (Dermal Papilla Cells), which in turn signal the hair follicles to return to the anagen phase of the hair growth cycle. Once in the anagen phase, the follicles begin to produce hair again.

In studies on mice and humans, and tissue studies from both animals, PRP jump-starts hair growth in dormant follicles (telogen phase) and increases hair thickness (diameter) of the individual shafts. Both of these findings support the idea that PRP returns hair follicles to the anagen (growth) phase.

In addition to re-growing hair, no significant or systemic side effects have occurred from PRP hair restoration therapy, or as Kang et al. put it, “PRP preparation has a positive therapeutic effect on male and female pattern hair loss without remarkable major side-effects.”

The cost of PRP versus other hair loss therapies

PRP hair restoration therapy: $1,000 – $2,500 per treatment

PRP therapy for hair restoration and rejuvenation involves injecting platelet rich plasma into the scalp.

At Great Alchemy, we perform three treatments about a month apart to ensure maximum follicle activation. Each treatment involves a series of PRP injections into the scalp. (Don’t worry. We anesthetize the scalp first.) We also add a vasodilator to the PRP to enhance its absorption into the skin.

These injections are followed by a topical application of PPP (the remaining portion of the plasma, called “platelet poor plasma”), which penetrates the upper dermal layers thanks to a device called a dermal roller. This micro-trauma invigorates the scalp and recruits the body’s natural healing response, which further activates the PRP. The entire procedure takes about an hour.

Although the effects of PRP hair restoration therapy are not immediate, patients begin to notice a substantial difference after about a month. At first, the new hair is light-colored fuzz, but gradually each hair shaft becomes thicker, darker, and longer, until the follicles begin producing their own natural hair — without surgery and at a fraction of the cost.

The beauty of using PRP for hair restoration is that this type of therapy is regenerative: It continues working for months — even years — after the initial injections. In other words, once the PRP stimulates hair follicles into the growth (anagen) phase, the follicles often return to their youthful growth cycle.

I suggest that my patients return once a year for a PRP booster treatment to reinvigorate their scalp and keep their hair looking young and healthy.

Hair Transplant (follicular unit extraction): $4,000 – $15,000 depending on the number of grafts

PRP hair restoration therapy works best in areas where hair is thinning but not absent. When hair follicles become severely atrophied after being dormant for many years, they are often beyond PRP’s power to regenerate. In these cases (mostly bald men who have not had hair growth for a long time), follicular unit extraction (FUE) is considered the gold standard for hair restoration.

Interestingly, for years, hair transplant surgeons have been using PRP to increase the survival rate of transferred follicles and aid in the healing process.

The barrier of entry for hair transplants is usually the cost. We all want to look young and beautiful; however, $10,000 or $15,000 buys a really nice used car or covers a year of in-state college tuition. Even for those who are blessed with the means to afford a hair transplant, I recommend trying PRP therapy first because you may get the results you’re looking for and save yourself a lot of money.

Finasteride (Propecia, Proscar): $60/month ($720/year)

Finasteride is an oral prescription medication that helps regrow hair by interrupting the conversion of testosterone to dihydrotestosterone (DHT). Finasteride does this by inhibiting the 5-alpha-reductase enzyme necessary for the conversion of testosterone to DHT.

Finasteride’s hair growing properties were discovered during clinical trials for men with enlarged prostate. (DHT also has a powerful effect on prostates.) When the drug started regrowing hair for the men in these trials, the researchers at Merck realized they had an even bigger market for this new medication in male hair loss.

For 85 percent of the men in these clinical trials, finasteride stopped hair loss, and 65 percent reported new hair growth. The American Hair Loss Association recommends Finasteride as a first line of defense against hair loss.

In addition to regrowing hair and reducing enlarged prostates, Finasteride also carries a 30 percent reduction in prostate cancer for men who take a 5mg daily dose.

Although rare, side effects of finasteride include erectile dysfunction, ejaculation disorder, decreased libido, anxiety, and depression. In 2012, the FDA added to warning labels that these side effects may continue indefinitely after a man discontinues taking finasteride.

So men need to weigh the potential loss of sexual potency and their sense of drive against hair regrowth and a decreased chance of developing prostate cancer.

Women who are pregnant or may become pregnant should NEVER handle finasteride tablets because of the potential risk of birth defects in a developing male fetus if this medication is absorbed through the skin. This concern is not an issue for women who do not wish to have children or are past their childbearing years.

Rogaine (minoxidil): $50/month ($600/year)

Rogaine is effective at stopping hair loss, especially if used early enough. According to WebMD, minoxidil enlarges hair follicle diameter and stimulates new hair growth. Seven out of 10 men who use Rogaine say that they regrow some hair. The downside of Rogaine is having to use it twice a day. In some cases, Rogaine irritates the scalp and causes itchiness, flaking, and redness.

Rogaine also takes from four to six months to show results. Many men become discouraged and give up on Rogaine before it actually starts to work. In some cases, Rogaine initially promotes the transition from the telogen phase to the anagen phase — so hair follicles release their hair strands before starting to grow new ones. This transition may appear as if Rogaine is causing hair loss, when it is actually stimulating the growth of new hair.

Rogaine does not regrow hair in bald spots or replenish receding hairlines.

Bottom Line

Bald can be beautiful, but beauty is in the eye of the beholder. If hair loss doesn’t fit the look you want or the lifestyle you have — don’t worry, you have options:

  • PRP provides long-term hair re-growth and restoration — without side effects or draining your bank account.
  • Hair transplants are very successful and very expensive.
  • Finasteride also works well (and protects against prostate cancer) but in rare cases can cause sexual and psychological side effects.
  • Rogaine works if you want to keep the hair you have or thicken it slightly.

If you’re concerned about hair loss (or know someone who is), please contact me at 303-554-4444 for a complimentary consultation so we can design a hair restoration plan specifically for you.

Can PRP from your own blood rejuvenate your skin and eliminate wrinkles?

By | Blog, PRP, women's health

By Dr. Emilia A. Ripoll, M.D.

If the title of this article sounds like the plot of an episode from the HBO series True Blood, I assure you it’s not.

The title refers to a relatively new form of skin care called Platelet Rich Plasma or PRP.

PRP is derived from your own blood and has been used successfully for over 30 years in countless procedures around the world — including dentistry, orthopedic surgery, and sports medicine.

The list of professional athletes who have benefited from PRP treatments reads like a who’s who in pro sports: Rafael Nadal, Tiger Woods, Kobe Bryant, Troy Polamalu, Andre Johnson, Nelson Cruz, Ray Lewis, Hines Ward, Fred Couples, Cliff Lee, Takashi Saito, Michael Young, Jonathan Bornstein, Tracy McGrady … the list goes on.

In addition the “headline grabbing” world of professional sports, the benefits of PRP have also been applied very successfully to anti-aging and skin-rejuvenation procedures. In this application, PRP injections cause the skin to produce more collagen and keratin and repair everything from acne to scars to wrinkles — even stretch marks.

The results are incredible and typically last between 12 to 18 months, and there is also a cumulative effect from these procedures. In addition, PRP therapy is 100 percent natural (autologous), and it is performed in doctor’s office in about an hour.

What is PRP and where does it come from?

Blood is made up of four major components: red blood cells, white blood cells, plasma (lymph), and platelets. The “cellular” portion of blood is composed of 91 percent red blood cells, 6 percent platelets, and 1 percent white blood cells. Plasma is the straw-colored medium within which all the other components are suspended. Plasma is what allows blood to be fluid. Without plasma, the heart wouldn’t be able to pump the remaining slurry of cells, platelets, proteins, hormones, waste products, and other molecules.

Platelet rich plasma is exactly what the name implies: plasma that contains a higher-than-normal concentration of platelets. Injecting plasma that contains 4-8 times the normal amount of platelets into and around ageing or injured tissue promotes rejuvenation and healing — regardless of when the problem is or when it started.

How Does PRP Eliminate Wrinkles?

Platelets accelerate healing by releasing several different classes of bioactive molecules such as growth factors and glycoproteins, which jump-start tissue repair and regeneration. When it comes to healing injuries, platelet-derived growth factors and glycoproteins do the heavy lifting.

These bioactive molecules initiate tissue repair and rejuvenation on a cellular level by activating local stem cells. The stem cells, in turn, stimulate the growth of new collagen and keratin by signaling the fibroblasts and keratinocytes in the dermal layer of your skin to produce more collagen and keratin respectively. Once the underlying support structures in the dermal layer have been sufficiently repaired, it smoothes the peaks and valleys in this deeper skin layer.

The net effect of this rebuilding process is that PRP heals scars, acne, pockmarks, wrinkles, lines, burns, stretch marks, and skin folds from the inside out. This healing occurs regardless of the area of concern: face, neck, hands, arms, legs and so on. PRP injections even improve the healing of diabetic ulcers.

PRP also enhances blood flow to the in and around the injection site(s) through the formation of new capillaries and blood vessels (angiogenesis), which enhances and accelerates the wound-healing process.

The science behind PRP

My patients often ask me if I think PRP will work for their cosmetic and aesthetic issues. My initial answer is almost always “yes.” And I make sure they understand that the exact level of restoration/regeneration depends upon the individual.

What gives me the confidence to say “yes” is that while PRP therapy has been used successfully for many years in wound healing and skin rejuvenation. Also, numerous medical scientists, dermatologists have studied PRP’s effect on wound healing and aesthetics — and the data is compelling.

For example, a 2010, study published in the French Journal Le Journal de Médecine Esthétique et de Chirurgie Dermatologique reviewed the data from three international studies of PRP on facial rejuvenation (in Japan, the UK, and Israel). Despite their differences, all three studies demonstrated convincing results.

As the articles’ author, Dr. S. Zenker concludes, “Both superficial and deep dermal applications can result in skin rejuvenation and global facial volumisation. PRP is a form of biostimulation that is safe and creates an immediate, long lasting volumetric effect with natural looking results. The technique is easy to perform and has virtually no side-effects.”

The key words in Dr. Zenker’s quote are: safe, immediate, long lasting, and no side-effects.

If you are thinking about some form of facial rejuvenation of wrinkles, skin folds, crow’s feet or the regeneration of new tissue to erase acne, pockmarks, or facial lacerations Dr. Zenker’s words ought to be music to your ears.

Although PRP is an amazingly effective form of therapy, it does have its limitations. It won’t make an elderly woman look like she did in her senior prom pictures. However, it can dramatically diminish the appearance of wrinkles, acne scars, and facial lines. The degree to which the wrinkles, lines, and scars disappear depends upon a number of factors including age, overall health, number of treatments, and how each person’s body responds to treatment.

Evaluating PRP

When evaluating whether PRP is right for my patients, I ask them to consider the alternatives. Facelifts are very invasive, quite expensive, and often effective. Fractional laser treatments are also expensive and leave you looking like you spent the night in a tanning booth; however, the results can be quite effective. Botox® and volumising facial filler injections create striking results and are relatively inexpensive per treatment, but as with Cinderella, the clock strikes midnight all too soon, and then it’s time for another round of injections. Over time, Botox®  and facial filler injections can also weaken the collagen and keratin in your skin; whereas, PRP injections, strengthen the skin by rebuilding the collagen-keratin matrix and stimulating the local stem cells to produce more of these and other vital tissues for healthy skin.

Because PRP uses your body’s own tissues (platelets suspended in plasma), it is inherently safe. It is relatively non-invasive (the injections are given with very fine needles), and the only side effects are at the injection sites (tiny spots of blood and perhaps some minor bruising). The cost is a fraction of more invasive procedures, and you walk out of our office in about an hour.

For the first 12 hours, the only way anyone would know that you had a procedure done is that your face is rosier than usual. The effects also take shape gradually over the first three weeks as your skin rebuilds itself. It’s so gradual that people will wonder what you’ve done to look so much younger.

If the information I have provided here sounds promising, I recommend that you make an appointment for a consultation and see if PRP skin rejuvenation is right for you. I can be reached at Great Alchemy at 303-554-4444.

The O-Shot™ Is like Viagra for Women — Only Better

By | Blog, PRP, women's health

By Dr. Emilia A. Ripoll, M.D.

Since the dawn of time, the desire for sexual pleasure has been the magnetic attraction that pulls couples together. This desire fuses virility and fertility to create families, clans, communities — and hold them together.

The decline of this desire, however, has led to the demise of untold billions of relationships, marriages, and families. The question about what to do when the body’s ability to give and receive sexual pleasure interrupts the physical intimacy between two people is one that has been with us for millennia.

Since the invention of Viagra in 1994, millions of men with erectile dysfunction have regained their ability to have and maintain an erection (and their sex lives), and that’s a great thing.The kiss

But what about the woman?

Most men are ready to rock ‘n roll after taking Viagra or Cialis, but if the woman is “of a certain age” (or there are other issues), she might also need a little something in the romantic intimacy department too. And “Viagra for women” does not exist.

Thankfully, Dr. Charles Runels, M.D. has pioneered an ingenious application of PRP (Platelet Rich Plasma) therapy called the O-Shot™ — which is even better than Viagra for women could ever be.

Dr. Runels and other O-Shot™ trained physicians have helped thousands of women achieve renewed levels of sexual pleasure and intimacy — not to mention curing stress incontinence in more than 90 percent of women.

As a urologist and urologic oncologist, I have been doing vaginal injections for over 25 years, so I have a high level of confidence and expertise with this procedure. Couple that with women in Boulder County being some of the healthiest the country, and I suspect we will soon see amazing results.

Gathering PRP for the O-Shot procedure

As with all PRP procedures, the O-Shot™ begins with a couple of vials of blood being drawn. The plasma that contains the PRP is then separated from the red and white blood cells by a centrifuge. The platelets, which contain highly active glycoproteins known as growth factors (also called “chemokines” and “cytokines”), are then injected with an extremely thin needle (27 gauge) directly into the anterior wall (roof) of the vagina and into the clitoris and the surrounding tissue. (Before you blanch at the prospects of vaginal and/or clitoral injections, the entire vaginal area is numbed with a topical cream before the injections, so the patient feels no pain.)

The chemokines and cytokines within the PRP stimulate the local “uni-potent” stem cells (stem cells that only produce new cells in the adjacent tissue), which in turn initiates the production of new tissue in and around the injection locations. The growth factors within PRP stimulate the productions of new cells, enhance the migration of these cells in and around the injection sites, repair damaged cells, and extend the life of existing cells — all of which contribute to tissue rejuvenation.

PRP injections also enhance the proliferation of fibroblast growth factors (FGF) that direct the formation of new blood vessels and capillaries (angiogenesis) and wound healing.

As with wound healing, the rejuvenation of the roof of the vagina and the clitoris involves numerous tissue types (blood vessels, nerves, smooth muscle fibers, lymph vessels, connective tissues, endothelium and so on). So when the body, in this case the vagina and the clitoris, receive a concentrated pulse of bioactive glycoproteins and FGF from a PRP injection, they immediately begin the process of generating new tissue.

“It is this rejuvenated tissue that is responsible for the female sexual response,” Dr. Kevin Aister, M.D. of Scottsdale, Arizona told Fox News in January 2013.

The O-Shot

The O-Shot™ regenerates vaginal tissue and rejuvenates the female sexual response. It also eliminates female stress urinary incontinence in more than 90 percent of cases. In addition, the only reported side effect of this treatment is some occasional spotting right after the injections, which goes away completely in 12 hours.

Here are just a few of the benefits regularly reported by women who have had the O-Shot™:

  • Increased sexual arousal and desire
  • Improved natural vaginal lubrication
  • Reawakened feelings of bonding with their partner
  • More frequent orgasms
  • Stronger orgasms
  • Virtually eliminates stress incontinence (in more then 90% of cases)
  • Decreased pain during intercourse (if there was any before)
  • Minimal, if any, side effects
  • Takes one-three weeks to see results; full effects achieved within three months
  • Effects last a year or longer
  • Compared to other treatment options for stress incontinence and female sexual dysfunction, this non-surgical procedure is relatively inexpensive (approximately $1,500).

When it comes to the safety of the procedure, a 2012 article in the journal Arthritis Research & Therapy sums up the current thinking about PRP therapy: “To date, there is no compelling evidence of any systemic effect of local PRP injections.”

According to Dr. Runels, “What’s amazing to me is that approximately 40 percent of women in this country have stress urinary incontinence problems, but no one is willing to talk openly about it… How many physicians can say to their patients, ‘Come to my office on your lunch break, and you’ll walk out with zero stress incontinence?’”

The combination of feeling sexually awakened and free of any worries about leaking urine is truly liberating. And it all comes from a simple series of injections.

As a final point, I should add the targeted injection sites for the O-Shot require expert precision. If the physician misses the target injection sites, the desired results will not occur. Because of the level of skill involved, this is not a medical procedure that should be left in inexperienced hands. With more than 25 year of experience as a urologist and urological oncologist, I know where to go. I would also be delighted to discuss whether the O-Shot™ is right for you.

For additional information about the O-Shot™, please contact Gr8Alchemy at 303-554-4444 visit Dr. Runel’s Web site and be sure to look for the February edition Harper’s Magazine for an article about Dr. Runels and the O-Shot™.

The Priapus Shot Enhances Sexual Performance and Delivers Measurable Male Enhancement

By | Blog, PRP

By Dr. Emilia A. Ripoll, M.D.

Throughout ancient history, people worshiped fertility gods and goddess in hopes of fulfilling their desire for sexual intimacy and pleasure, as well as increasing their virility and fertility: Priapus in Greek mythology (see image), Isis and Min in Egyptian mythology, Lakshmi/Bhumi in Hindu mythology, Kokopelli in Native American mythology, just to name a few.

In more recent times, men (and some women) have sought the benefits of various herbs, bones, horns, and the flesh of certain animals to help restore their waning sexual potency and performance. Ginseng, tiger bone, rhino horn, oysters, and the genitalia of large powerful mammals (Rocky Mountain oysters) are some common examples of this practice.

A big shift in treating what we now call “erectile dysfunction” happened in 1994 when the Pfizer pharmaceutical company in England sent representatives to investigate why certain priapusvolunteers in the Phase 1 clinical trial for sildenafil citrate (an experimental heart medication) refused to return their unused allotment of meds once the trial was over.

When researchers discovered that this medication was of little value in treating angina or hypertension, but had a huge affect on men’s ability to have and maintain an erection, they understood why.

Two years later, sildenafil citrate (trade name: Viagra) was patented. Today, Viagra has been prescribed for over 40 million American men, and U.S. sales top $1 billion annually.

There’s no argument that Viagra, Cialis, Levitra, and other medications for erectile dysfunction have helped many millions of men regain their sex life — and that’s a good thing.

However, taking a prescription drug everyday or in anticipation of having sex falls short of being erotic. In addition to problematic side effects, managing your prescription, regular trips to the doctor’s office and the pharmacy, and feeling romantically dependent on a medicine bottle can all interfere with a man’s mojo.

Fortunately, Dr. Charles Runels, M.D. recently pioneered an ingenious application of PRP (Platelet Rich Plasma) therapy called the Priapus Shot™, which has helped thousands of men achieve new levels of sexual potency, performance, and pleasure. In addition, more than half the men who receive the Priapus Shot™ report measurable penile enhancement.

After 25 years of doing penile injections to help men overcome severe erectile dysfunction, I was very impressed by the results other physicians were having with the Priapus Shot™ — so much so that I became a Priapus Shot™ practitioner.  This quarter century of experience gives me many times more than the 10,000 hours that Malcolm Gladwell claims are required to develop mastery of a particular skill.

What is the Priapus Shot?

Named after the Greek god of fertility, the Priapus Shot™ is a series of six penile injections that rejuvenate a man’s ability to get and maintain an erection. These injections restore proper blood flow into and out of the penis and boost erection quality by a staggering 98 percent!

Here are a few of the improvements Dr. Runels’ patients report:

  • Better quality of erection (5-point increase on the 25-point scale used by doctors)
  • Sixty percent report an increase in at least a ½ inch in penis length and girth
  • Feeling like you’ve turned back to clock on your love life
  • Dramatically increases blood flow to the penis by opening the small arteries and capillaries without creating systemic vascular side effects like Viagra and other medications
  • Since PRP is derived from your own body, there have never been any reported systemic side effects.
  • Takes one-three weeks to see results; full effects are achieved within three months
  • Effects typically last over a year.
  • Compared to other treatment options for erectile dysfunction and penis enlargement, this non-surgical procedure is relatively inexpensive (approximately $1,500).

How PRP Works

As with all PRP procedures, the Priapus Shot™ begins with a couple of vials of blood being drawn. The plasma that contains the PRP is then separated from the red and white blood cells by a centrifuge. The platelets, which contain highly active glycoproteins known as growth factors (also called “chemokines” and “cytokines”), are then injected with an extremely thin needle (27 gauge) directly into these six injection areas. (Before you squirm at the thought of penile injections, the entire penis is numbed with a topical cream before the injections, so the patient feels no pain.)

The chemokines and cytokines within the PRP stimulate the local “uni-potent” stem cells (stem cells that only produce new cells in the adjacent tissue), which in turn initiates the production of new tissue in and around the injection locations. The growth factors within PRP stimulate the productions of new cells, enhance the migration of these cells in and around the injection sites, repair damaged cells, and extend the life of existing cells — all of which contribute to tissue rejuvenation.

PRP injections also enhance the proliferation of fibroblast growth factors (FGF) that direct the formation of new blood vessels and capillaries (angiogenesis) and wound healing.

As with healing any wound, the rejuvenation of the penis involves numerous tissue types (blood vessels, nerves, smooth muscle fibers, lymph vessels, connective tissues, endothelium and so on). So when the body, in this case the penis, receives a concentrated pulse of bioactive glycoproteins and FGF from a PRP injection, it immediately begins the generation of new tissue in the corpus cavernosa and throughout the entire penis.

Think of PRP as the fertilizer that restores a tired garden back to its former verdant luster.

The Origin of the Priapus Shot

Dr. Runels created the Priapus Shot™ on the heels of his success with his first signature PRP procedure, the Vampire Facelift™.

As Runels tells it, a salesman from a PRP kit manufacturer came to visit his office and told him, “Dr. Runels, I see you are doing a high volume of Juvéderm and Botox work. PRP works just like Juvéderm Juvéderm and Botox, and it causes increased volume and blood flow, with no side effects.”

“When he said ‘new volume and blood flow,’ the first thought that went through his mind was, this is going straight into my penis. I was thinking about male sexuality after all my work with hormone replacement therapy. I wanted to try it on my own penis first before I even thought about offering it to a patient.”

However, the lack of medical literature on such an injection, coupled with the fear of priapism and having to go to the emergency room to have his penis drained, kept Dr. Runels’ experimental desires at bay.

After about four months of pondering this idea, Dr. Runels received a call from San Diego. The man on the other end of the phone had read about Dr. Runels online, and asked if PRP could help improve the size of his penis. “He told me he was, ‘a conservative Jewish man with a small penis,’” Runels recalls. “’I am about to get married. I’m a good looking. I surf. I’m well traveled. I have a great business, but I’m worried that my finance might reject me because I have such a small penis.’”

And then he asked for help. Dr. Runels told his first potential patient that he would call him back within a week.

It takes a crazy redneck to try something like this

“I was very frightened,” Runels remembers. “What if the injection blocks off the blood flow, and I end up with priapism, necrosis, or some sort of weird curvature? I told my girlfriend, ‘You may need a new boyfriend soon, because if what’s I’m thinking about doing doesn’t work, you may not want to be with me anymore.’”

To help move the PRP around throughout his penis, Runels decided to employ a penis vacuum pump so the platelets wouldn’t pile up in one place.

“It takes a crazy redneck to try something like this,” Dr. Runels said of himself.

The crazier thing is it worked — extremely well

“From the combination of the injection and the pump, the base of my penis was clearly more substantial than it was before,” Runels said. “My girlfriend agreed. So we did a little experiment. And I had two thoughts: One, I wish I had a transcript of everything my girlfriend was saying so I could write it down for marketing purposes; and two, size really does matter.”

Dr. Runels called his potential patient in San Diego and told him, “You’ll be the first patient, and it may not work — or you could have a bigger penis in a month. Ironically, it did not make his penis larger. But he said that he doesn’t use the pump — it felt too weird.”

Dr. Runels has since discovered that the men who see the biggest gains in penis size are the ones who use the pump in conjunction with the injections. “It’s like taking steroids and lifting weights, if you don’t lift weights while you’re taking them, you won’t get any bigger.”

Despite the lack of increase in penis size, the San Diego patient was very please with the injections. “I asked him if he wanted his money back, and he said, ‘No, because my penis is working so much better now.’”

Since then, Dr. Runels has passed the torch to a select group of physicians like myself. Now, we are using the Priapus Shot™ to help our patients have the most meaningful sexual experience of their lives.

For more information about the Priapus Shot™, please contact my office at 303-554-4444.