PRP: Platelet Rich Plasma
PRP is a specific portion of your plasma that is separated from a vial of your blood in a centrifuge. PRP contains an unusually high concentration of platelets (5-10 times the number in normal blood), hence the name.
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Platelets are cell-like organelles (cells without a nucleus) that are essential to blood clotting. They also accelerate the wound healing process by signaling local stem cells to increase the production of new tissues (proliferation), which tissues (differentiation), directing the movement of these newly formed cells (chemotaxis), their shape (morphogenesis), the formation of new capillaries and vessels (angiogenesis), as well as healing damaged tissue on a cellular level.
Recent data indicates that platelets release a pulse of bioactive glycoproteins — commonly called “growth factors” (or more specifically as chemokines and cytokines).
These bioactive proteins are responsible for signaling your body’s microscopic repair mechanisms that is time to take action.
PRP was first widely used in dentistry in the 1980s to promote gum and bone healing in tissue surrounding new implants, jaw reconstruction, and gum regeneration procedures. For decades, PRP has been effective in several fields of medicine: sports medicine, orthopedics, dermatology, neurosurgery, ophthalmology, ENT (Ear, Nose and Throat), and cosmetic surgery.
Because PRP therapy involves using your body’s own plasma, there is virtually no possibility of rejection or an allergic reaction.
Likewise, since nothing foreign is being injected, the risk of infection is extremely low, especially since platelets are part of the body’s defense mechanism against unwanted microbes like bacteria and viruses.
There are also no know systemic (side) effects from PRP therapy, although it is normal to feel pain and swelling near the injection sites. This is part of the body’s healing process. This pain and inflammation usually peaks within 24 hours and disappears after a couple of days.
PRP for Facial Rejuvenation
Plasma Rich in Growth Factors to Treat an Articular Cartilage Avulsion: A Case Report
Platelet Rich Plasma for Hamstring Tears
Platelet-Rich Plasma: New clinical application: A pilot study for treatment of jumper’s knee
Platelet Rich Plasma in Prolotherapy
Platelet-Rich Plasma: From Basic Science to Clinical Applications
Autologous Fat Grafting as a Mesenchymal Stem Cell – Source and Living Bioscaffold in a Patellar Tendon Tear
Treatment of Chronic Elbow Tendinosis With Buffered Platelet-Rich Plasma
Platelet Rich Plasma in Rotator Cuff Repair
Prevention of Disc Degeneration with Growth Factors
Platelet Rich Plasma (PRP) Matrix Grafts
Treatment of Chronic Wounds with Autologous Platelet-Rich-Plasma
Platelet Rich Plasma Injection Grafts for Musculoskeletal Injuries: A Review
Biological Augmentation of Rotator Cuff Tendon Repair
Platelet-Rich Plasma Application During Closure Following Total Knee Arthroplasty
Treatment of Tendinopathy
Treatment of Tendon and Muscle Using Platelet-Rich Plasma
Use of Platelet Growth Factors in Treating Wounds and Soft-Tissue Injuries
For additional information about PRP therapy, please see the other PRP pages on this Web site or contact Great Alchemy at 303-554-4444.